Pet club of former Super Eagles star Nwankwo Kanu, Papilo FC, sent packing Nigeria National League side Gombe United from the Federation Cup on Thursday after a 3-2 win.
NPFL sides Giwa, Sunshine Stars and Shooting Stars all lost to small teams in the round of 64 games.
Premier league side Taraba thrashed Akampa United 3-0 in another cup tie on Thursday.
Coach Tony Ogharanduku boys got the first goal through Chinedu Ohananchom, who connected a cross from the right wing with a header in the 10th minute.
Ibrahim Sanusi made it 2-0 for the Jalingo-based team in the 36th minute.
He completed his brace with the third goal when he jabbed in a cross from the right flank in the 85th minute.