Tag: Stella Ugbobuaku

  • Strengthening Africa’s clinical research ecosystem amid global disruption

    Strengthening Africa’s clinical research ecosystem amid global disruption

    In a year defined by the global health crisis, Stella Ugbobuaku emerged as one of Africa’s foremost champions of clinical research resilience and reform. While many institutions struggled to maintain trial operations during COVID-19 lockdowns, Stella helped turn disruption into an opportunity to reimagine research infrastructure and equity across the continent.

    At the heart of her 2020 achievements was her leadership in regional collaboration. Through LASUTH’s Public Health and Trials Unit, Stella facilitated partnerships with counterparts in Ghana, Kenya, and Sierra Leone to share protocols for safe and adaptive clinical research under pandemic conditions. 

    These partnerships led to the launch of the West African Clinical Trial Continuity Initiative (WACTCI), which has since been credited with helping over 20 critical studies resume operations safely and ethically.

    Her voice was especially prominent in virtual forums. In July 2020, she delivered a keynote at the Africa Research Ethics Network Conference, where she presented her Rapid Site Risk Index Model—an innovation that helps institutions assess when and how to safely restart clinical trials after public health disruptions. This model is now in use across four West African countries.

    Stella’s approach is grounded in accessibility. Recognizing that many African sites lacked digital infrastructure for trial continuity, she co-developed a low-bandwidth eMonitoring Toolkit that allows ethics committees and sponsors to remotely monitor data, patient safety, and protocol adherence using mobile-based systems. The toolkit has been deployed in rural research settings in Kwara and Cross River states, Nigeria, with remarkable success.

    Beyond tools and models, her advocacy for equitable trial access deepened. Stella led an evaluation of COVID-19-related trials in Nigeria, identifying disparities in participant representation and site selection. Her findings informed a policy brief submitted to the National Health Research Ethics Committee (NHREC), calling for more inclusive, geographically diverse trial design moving forward.

    Her work continues to inspire a new generation of African research leaders. 

    Through her mentorship program for young investigators, Stella provided virtual training and one-on-one coaching to over 60 early-career professionals in 2020, many of whom are now leading their own research teams.

    “Stella is a systems builder,” remarked Dr. Adeola Sanni, Director of Research at the West Africa Health Organization. “She’s not only thinking about today’s trials—she’s laying the groundwork for Africa’s research future.”

    As the world confronts the challenges of a post-pandemic landscape, Stella Ugbobuaku’s work remains a beacon of possibility. She is proving that clinical research in Africa can be both excellent and equitable—and that leadership grounded in purpose can withstand any crisis.