Tag: Tuberculosis

  • Tuberculosis and some other breathing problems

    GIRD your loins … tuberculosis is sweeping through the land, killing as many as 400 Nigerians every day, and roaming, inactive, in the bodies of more than 300,000 people it is yet to hack down. The government requires billions of Naira in this tight economy to contain the upsurge and spread of tuberculosis. As the money is not easily forthcoming, traditional medicine and alternative medicine will be the last resort of many sufferers and those who will be seeking protection against infection. There is, indeed, hope for such health seekers.

    I am on standby inside me these days whenever anyone around me is coughing. The possibility of infection is enormous in buses. Many people do not cover their mouths. Many others are not brought up at home or trained at school in the culture of handkerchief. So, shaking hands with an infected person, who covered his/her mouth with his/her hand while coughing can easily cause peril to other people, who come in contact with this hand. Not only that, dropplets of saliva which bear the mycobacterium tuberculosis, the germ which causes tuberculosis, may fall on another person’s clothes or skin. Back home, these germs may find their ways into the bodies of many people through food or contact.

    There have been cases where tuberculosis is spread or contracted by humans from cats, some fish and even red meat. I suspect that cow meat may be a major vector in Nigeria. Cows are headed through forests day and night under very stressful conditions, which deplete their immunity by the time they arrive at the abattoir for slaughter. In Lagos alone, about 10,000 cows are slaughtered every day. This is a lucrative business, which balloons every year. So, it may not be out of place to assume that, today, the Lagos abattoir may be dealing with about 15,000 cows every day. At about N150, 000 for a cow, the arithmetic should add up to N2, 250,000,000(two billion, two hundred and fifty million naira only) every day. This may be worth more than the value of petroleum products consumed in the city of Lagos every day, and suggests why cow herding through farms have become such a huge political question, which the herders protect with AK 47 guns. That is an aside, really. Where we are heading is that cows are required by law to be certified fit for human consumption before they are slaughtered at the abattoir and sold there or anywhere. The certification is to be done by veterinary doctors. To carry out this job efficiently, there must be enough veterinary doctors on stand-by.

    I imagine this would involve elaborate checks, including blood tests e.t.c. For 15,000 cows to be tested every day, the Lagos abattoir would require 150 veterinary doctors and their assistants, each working on about 100 cows. But is it possible for one vet doctor or one vet assistant to attend efficiently to 150 cows in one day? Your guess is as good as mine. Some infected cows would pass through the eye of the needle! And this may be one reason tuberculosis has again become a big deal in Nigeria, especially in the urban areas where cow meat is not properly cooked in food canteens. When I was a boy, women always boiled meat and then fried it before they cooked it in stew or sauce. In today’s canteens, the cook avoids this long process to prevent the beef from shrinking and losing economic value. Do not get me wrong. I am not, by this, advocating frying, because when proteins are overheated, they transform into nitrosomes, which can cause cancer. It is possible that the diet of those days gave rise to the wide range of cancer occurrences exhibited in the elderly of this generation.

    The Signs

    The symptoms of tuberculosis are not too difficult to know. Persistent coughing is, most likely, the primus inter pares. The cough type has the capacity to defy many fist-line pharmaceutical cough remedies. A second symptom is a streak or specs of blood in the sputum. Again, persistent night sweats may be observed. Then, there is a gradual weight loss, which the infected person or persons around him/her may mistaken for stress or poor diet. On top of these, serious damage to tissue may be going on inside the body. There is a mistaken notion that tuberculosis is, strictly, a lung disease. True, it predominantly features in the lungs. But it affects other organs as well. In earlier commentaries in this column, I explained how two of my male cousins from the same mother died of tuberculosis of the spinal bones, which eventually ate up parts of their livers, before it was discovered that the fever presented in those cases was not due to back pain alone. Tuberculosis may unleash some serious havoc, also in the adrenal glands, chest cavity, bones, throat, kidneys, eyes and even the sex organs.

     

    Mycobacterium Tuberculosis

    When the bacterium is “shelled” out of the mouth through amplest of saliva into the air or by coughing and spitting out the sputum, it mixes with dust. If this occurs in dry, hot weather, which threatens its existence, the germ would form a protective chiteneous material around itself to prevent dehydration and death. The snail, too, does this. The germ awaits the good day or time when wind would rouse the dust and some unfortunate person would inhale it. How many of us do not inhale dust? If the dust is infected, the germs get into us. We would be lucky if our immune systems, defenders of our bodies, would knock them out. This job falls largely on the macrophages, the large white blood corpuscles, which engulf and eat up germs, and are then killed themselves. If the macrophages are healthy and many and the immune system can produce as many of them as are needed during such an emergency as this, the battle is won without the infected person knowing that anything is going on inside his/her body. But if the macrophages die, and the bacteria they engulf survive them for no reason or another, these germs travels through the blood circulation to safe havens, which they then colonise and damage inadvertently in the poisonous waste products of their metabolism and other activities. Sometimes, the body may have successfully boxed them up in cages, so to say, in which they are inactive, but the day stress overtakes the body and the immune system cannot keep an eagle watch, as during an HIV infection, the “cages” are thrown open in a sort of jail break, and the tuberculosis germ, once again, becomes ambulatory, that is free moving and infective.

     

    Treatment

    Doctors and pharmacists have struggled for hundreds of years to find a cure for tuberculosis and to even eliminate the germ. But many factors make this dream illusory. The victims are largely poor people, who live in overcrowded conditions in which the air content of oxygen is depleted. They do not eat well enough to give their body the protein it requires to form a formidable immune system. They over work to earn meager incomes, thereby stressing themselves. I encounter a big picture of the air pollution at Oshodi bus terminal everyday on my way home to Abule-egba by LAG BUS. The mini buses charge between 400 and 500 in place of 100 or 150 because heavy traffic has held down the big buses. Hundreds, if not thousands of commuters stand on their feet, all stressed up, for more than one hour, waiting for the traffic to move and for the big buses to come. Everyone, whether at the terminus platforms or in the stuck buses, is inhaling carbon monoxide instead of oxygen, ignorant that this would de-oxygenate their blood and that de-oxygenated blood does not support healthy immune system. They finish off their immune systems all the more when they arrive home and eat junk food and spray their bedrooms with dangerous anti-mosquito insecticides. what could be more disheartening in this regard than a story I heard on radio this morning (8 June 2018). A man and his wife who had just built a home in Shagamu, Ogun State, died in his house on their first night there. There were seven of them in one room. When their neighbour’s smelled stench coming from the house, they called the police, the police broke through the room and found seven decomposed bodies. It was speculated that they would have tried to clear rodents from the property with a powerful insecticide. Among poor Nigerians, SNIPER is widely used for the purpose despite many warnings to the contrary. Even in their single-bed apartments in face-me, I slap you, or face to face (apartment) single-bed houses, some cook in their rooms, or inhale petrol fumes when their neighbours refill the tanks of their “I better pass my neighbour” electricity generating sets. All these factors and more pre-dispose many people to tuberculosis infections and attacks and to the failure, sometimes, of pharmaceutical drugs. Accordingly, and especially because some strains of tuberculosis are becoming resistant to these drugs, some doctors now prefer to add chemotherapy to their treatment regimen. Even this has many side effects, which are now well known. To the doctors’ prescriptions, traditional medicines and alternative medicine protocol may be used as adjunct to conventional treatment or for prophylactic (prevention) purposes. The recipes, which I will mention hereafter have been used by some orthodox doctors either alone or as adjunct medication, with successful result. They have been found useful, also, in other pulmonary (lung) or breathing problem such as asthma, congestive obstructive pulmonary disease (COPD) and emphysema, to mention a few of them. The therapeutic goals in employing them revolve around, as usual, detoxification, alkalisation, mineralisation, oxygenation, parasite killing and immune boosting, among other objectives. An acidic system weakens the immune system and disorient it, whereas an alkaline system does the opposite, there are herbs, which stimulates the excretory organs (the lungs, liver, kidneys, skin and the bowels) to empty their toxic wastes for evacuation, and there are anti-oxidant, and there are anti-oxidant herbs, which destroy free radicals in the toxins, to prevent their overload in the blood during detoxification from mauling the system.

    I would like to begin with Astragalus, which has demonstrated the capacity to help the body produce more macrophages. Zinc is useful in more than 250 ways for equilibrium the body biochemical processes. Women know it is good for hair, skin and nails, robust breasts, fertility and all that. Many men, too, have found it helpful to combat prostate gland challenges and improve sperm count and sperm health. Without zinc, there is little vitamin A can do for healthy vision. In its immune system function, zinc helps the Thymus Gland to maintain its size and efficiency. It is inside this gland that T-Cells or fighter cells mature. It is like their finishing defense academy.

    I doff my heart for Golden Seal Root, one of nature’s most dependable antibiotic, antiviral and antifungal herbs. Maria Treben, that great Austrian herbalist of blessed memory, eulogised Calamus root for practically all health needs, including tuberculosis in her HEALTH THROUGH GOD’S PHARMACY Mark Treben says: “A year ago, a man 1.8 meters tall in his late fifties had become a skeleton without knowing the reason for his illness. Weighing only 45 kilos, he in company of a nurse stepped into the surgery of his doctor, who was telephoning another doctor and heard: I am sending you my most hopeless-patient … cancer of the lungs: so unwittingly the man learnt the diagnosis of his illness”. Afterwards, someone advised him to chew Calamus root to break his smoking habit and to drink yarrow tea mornings and evenings. Slowly, his weight increased, and since he felt better, he did not return to the doctor. About half a year later, he again went to the surgery of the doctor, who was most taken aback since he had thought this man dead. What did you do?, was all he could say. “Chewed Calamus root and drank yarrow tea”, replied the man. ‘ Calamus root? . Where did you find them? They are sold in herbal shops for a few shillings’. The man at this time reached his normal weight of 86 kilos and it was half a year later that he undertook a mountain hike, carrying a full laden back pack when I met him.’

    The book, which I recommend for your health library, tells, also, the story of a man aged 36 years, who literally lost his balance after surgery to free the liver of a tumor. He was thin and went to develop tuberculosis in the intestine. Calamus root helped these conditions as well, reported Maria Treben. There are other startling cures achieved in the stomach and intestinal disturbances, including cancers. To Calamus and Yarrow we may add her suggestion of Horse Tail. I guess this is because of the high Silica content of this herb. Silica, called the homeopathic surgeon because it breaks up growths, is now available in 100 per cent biochemist tissue or cell salt No 12 and 96 per cent in Diatomaceous Earth (DE) or Diatom. Stinging Nettle has small amount of it.

    We cannot address all useful remedies. Before I move on to Dr. Robert Atkens, one of those conventional doctors, who made the United States adopt nutritional food supplements. I would quickly like to add to the list Grape Seed Extract (GSE), which is highly antioxidant and one of those few supplements substances, which easily cross through Brain Blood Barrier. Dr. Raymond Strand reports that a man, who declined chemotherapy and opted instead for dietary supplements, especially GSE, normalise his Anti-Nuclear-Antibody (ANA) results within one year. His ANA had risen well over 1,000 per cent of normal. Dr. Strand mentioned this case in his “What Your Doctor Does Not Know About Nutrition May Be Killing You.”

    Let’s hurry to Dr. Robert Atkins. Among his suggestions for all lung diseases is vitamin A. But, like all doctors, this mega-dosage physicians will not touch regular (i.e. oil soluble) Vitamin A with a long pole. Not more than 5000 I.U of it every day is often suggested, to prevent liver discomfort or damage, and birth defects. Dr. Atkins, like many physicians, prefer the water soluble variant of Vitamin A. which is often mentioned in this column as solubilised or water soluble Vitamin A. Dr. Atkins calls it by its other name.

    Mycellized Vitamin A, saying: “If your body’s Vitamin A stores must be replenished in a hurry, as would be necessary at the outset of an acute respiratory infection, use the mycellized version, which by-passes the liver and is absorbed easily, thus reducing the likelihood of a toxic accumulation. Even in amounts of 100,000 I.U a day, for months at a time, mycellized Vitamin A has never caused any documented side effect. This safety record does not mean, however, that therapeutic dosages need not be mentioned by a doctor. Mycellized A performs impressively against sinus and other acute infections, especially when combined with mycellized Vitamin E.’’ Dr. Atkins suggests carotenoids, not just Beta Carotene, a mere member of the 600-member plus family, which is offered today for even cancer prevention and cure, except lung cancer caused by smoking, which at least, one study has shown is worsened by it. It warns against synthetic Beta Carotene in particular, saying it has been found to lower the blood presence of other caroteneoids. One of such affected caroteneoids is Lutein, which is needed for healthy eyes and crucial in “glaucoma” management. He salutes “natural” beta carotene, a deficiency of which he says has been linked to many cancers, including that of the lungs, and says it works best when it is combined with, say, mycellized Vitamin A and other natural carotenoids.

    Maria Treben has an interesting handle on emphysema as well as cardiac asthma and disorders of the thyroid gland with their shortness of breath and is caused largely through liver trouble. The upward pressure of the liver contributes to the swelling and enlargement of the bronchial tubes, lungs and the heart. The constant pressure on the sensitive thyroid gland causes abnormal changes. In such a case, one cup of common club moss tea is drank in the morning and swedish bitters is applied as a compress for four hours during the day. I will round off with Dr. Atkins. The lungs and bronchial airways of the body are amazing, but delicate tissues. They are assaulted daily with both outdoor and indoor pollution, not to mention cigarette smoke and the toxic chemical found throughout our environment. Compound this inflammatory insult with lack of anti-inflammatory nutrients such as fish oil and anti-oxidants in our diets and you will understand why asthma and other pulmonary problems are continually on the rise. Food allergies can also be involved.

    The bottom line approach for inflammation of the bronchial passage is to relax them with magnesium, protect them with anti-oxidants and reduce their exposure to environmental insults. He suggests Vitamin C, Vitamin A, essential oils formula, N-Acetyl cysteine, magnesium, Beta carotene, quercitine, selenium, taurine, Vitamin E and Co Q10.

  • Nigeria has 302,096 unreported TB cases, says minister

    There are 302,096 unreported cases of Tuberculosis (TB) cases in the country, the Minister of Health, Prof. Isaac Adewole has said.

    TB remains endemic in different parts of the world, leading to annual deaths of nearly one-and-a-half million people, mostly in developing countries. Over ten million new TB cases were estimated to have occurred globally in 2016.

    According to the 2017 Global TB Report,Nigeria is among  the 14 high burden countries for TB, TB/HIV and MDR-TB. The country is also ranked 7th among the 30 high TB burden countries and 2nd in Africa. Nigeria is among the 10 countries that account for 64 percent of the global gap in TB case finding. India, Indonesia and Nigeria account for almost half of the total gap.

    The minister said, “In 2017, the country notified only 109,904 out of the estimated 407,000 – all forms of TB cases (with treatment coverage of 25.8 per cent), leaving a gap of  302,096  comprising  undetected or detected but not notified  cases especially in non-DOTS sites.  In the same year, the proportion of Childhood TB was seven per cent of all forms of TB cases compared to 10 per cent recommended by the World Health Organisation (WHO). In addition, a total of 1783 DR-TB cases were notified out of the estimated 5200 DR-TB cases.”

    He revealed that the country’s  major drawback in the fight to eliminate TB, is low case finding for both adult and children as there are a lot of missing TB cases that were either not diagnosed or diagnosed but not reported.

    He noted that the TB burden is further compounded by the menace of drug resistance TB (DR-TB) and the HIV/AIDS pandemic.

    Adewole however noted that the country is making progress in the fight to eliminate the disease despite the shortcomings.

    He said, “May I inform you that we are making  progress;  Nigeria currently has 6,753 DOTS centres compared to 3931 in 2010. The total number of microscopy centres has risen from 1,148 in 2010 to 2,650 in 2017. GeneXpert machines installed in the country have increased from 32 in 2012 to 390 in 2017. Treatment centres for patients with DR-TB haveexpanded from 10 in 2013 to 27 in 2017. The number of TB reference laboratories has also increased from nine in 2013 to 10 in 2018. Over 90 percent of the TB patients notified in 2016 have documented HIV test results compared to 79 percent in 2010.”

    The ministry he said has gone ahead to develop a robust national strategy to fight the disease.

    “In our response to the burden of TB, the Federal Ministry of Health developed a robust National Strategic plan (NSP) for TB (2015 – 2020) as well as a framework to support the declaration of 2017 as a year of accelerating TB case finding and treatment in Nigeria. The implementation of the NSP for TB (2015 – 2020) though not without its limitations has  brought  noticeable  improvements in TB control activities.

    “To accelerate TB case finding, the country has now moved from passive to active case-finding in key affected populations, including PLHIV children, urban slum dwellers, prisoners, migrants, internally displaced people and facility-based health care workers, to target those most at risk for TB. Over 11,500 TB cases were detected through active house to house case search in 2017.”

     

  • World Tuberculosis Day: USAID pledges to support Nigeria

    The United States Agency for International Development ( USAID ) has renewed its commitment to assist the Federal Ministry of Health to find and treat thousands of missing tuberculosis cases in Nigeria.

    Ms Minal Amin, Group Lead, Tuberculosis and Resource Mobilisation, USAID Nigeria, made this known in Abuja while briefing newsmen as part of the activities to commemorate the 2018 World Tuberculosis Day.

    Amin said USAID has been supporting the government of Nigeria’s response to tuberculosis since 2003; adding that USAID had a shared goal with government on reducing tuberculosis related deaths and disability.

    She said the agency was committed to support the National TB and Leprosy Control Programme in reaching its ambitious goal of ending tuberculosis in Nigeria.

    She commended the minister of health, Prof. Isaac Adewole, for his giant stride of declaring 2017 as a year accelerated tuberculosis finding.

    According to her, the agency has expended over 100 million dollars to support TB response programme in the past 15 years.

    “We look forward to the continued partnership and relationship with the government of Nigeria in making significant strides on TB control,’’ she said.

    Prof. Dipo Ladipo, Chief Executive Officer, Association for Reproductive and Family Health (ARFH), said tuberculosis detection in Nigeria was running at a level about 17 per cent due to many reasons.

    He said ARFH was a principal recipient of the Global Fund, and the association was working with the National TB and Leprosy Control Programme to improve awareness on TB at national, state and local levels.

    Ladipo added that the association via a funding from Global Fund was also working to improve TB detection rate and refer suspected cases to diagnostic centres for treatment.

    He, therefore, urged the media and other key stakeholders to evangelise tuberculosis and make it more visible public health concern because of the magnitude of the problem and mode of transmission.

    While speaking on the theme of the 2018 world tuberculosis day, Ladipo said religious leaders should play a leadership role to support the government by disseminating information about tuberculosis in mosques and churches.

    He also urged government to increase domestic funding of the tuberculosis response programme and encourage local production of TB drugs, stressing that most of the TB drugs in Nigeria are provided by donor agencies.

    According him, the TB partnership in Nigeria has worked tirelessly to reach the level where we are now; we require additional funding from the government to complement what the donors are doing.

    Dr Adebola Lawanson, National Coordinator, National Tuberculosis and Leprosy Control Programme, said Nigeria has the highest burden of tuberculosis in Africa and it was ranked seventh in the world.

    Lawanson, represented by Muhammad Ahmad, a Deputy Director, said the federal government in collaboration with partners provided quality patient centred prevention, treatment and support free of charge.

    She said in spite of interventions by government, 2017 WHO Global TB report revealed that Nigeria was among the 10 countries that accounted for 64 per cent of the global gap in TB case finding.

    “Nigeria alone accounted for almost half of the total gap.

    “In 2017, Nigeria notified a total of 104 904 TB cases which is only 26 per cent of the estimated 407,000 cases for the country in 2017,’’ she said.

    The 2018 world tuberculosis day would be observed on March 24, to commemorate the day in 1882 when Dr Robert Koch announced his discovery of the germ that causes TB diseases.

    NAN

  • Tuberculosis-infected inmate freed

    LAGOS State Chief Judge (CJ) Justice Opeyemi Oke yesterday released an inmate of Kirikiri Medium Security Prisons, Lucky Nelson, who is suffering from tuberculosis.

    But, she declined to release  14 others whose cases were  sent to her because they did not meet the criteria for pardon.

    Nelson, who has been in  custody since 2012 for allegedly obtaining  N25,000 by false pretence also has diabetes.

    On enquiry, a nursing officer,  who brought his medical file before the CJ said his case has defied medication.

    Justice Oke said Nelson was released on compassionate ground  and “to prevent the spread of tuberculosis amongst other inmates’’.

    “I also considered the period you have been in custody without trial. I want you to go out there, be of good behaviour and sin no more,” she said.

    Ten nursing mothers at the female section failed to meet the criteria for release.

    The CJ ordered the Director of Public Prosecution (DPP), Ms Titi Shita-Bey, and Director, Office of the Public Defender (OPD), Mrs Olubukola Salami and their officials to take the women’s data.

    She told reporters that  her visit was not just to release inmates but to ensure that those released deserves such reprieve.

    “Fourteen cases were presented to me for consideration but after interviewing them, I found that none of them merited to be pardoned. How can you release for instance, a child kidnapper or a murderer? That would be a disservice to the society.

    “It is very unfortunate but we must follow due process in releasing any inmate in the prison. Remember that members of the society must also be protected so we don’t just free any inmate without following due process,” she said.

    Earlier the Deputy Comptroller Prison (DCP) Oluwaniyi Emmanuel of Kirikiri Medium Prison, urged the  government to review the  huge fine imposed by the Task Force Mobile Court to avoid overcrowding of the prison.

    He said people had stopped helping offenders to  pay the fine.

  • Expert calls for increased funding for drug-resistant tuberculosis

    Expert calls for increased funding for drug-resistant tuberculosis

    The Federal Government has been urged to increase funding for fight against drug-resistant tuberculosis.

    The Associate Director Global Fund Programmes, Institute of Human Virology Nigeria (IHVN), Dr. Aderonke Agbaje, who made the call in Abuja in a meeting of more than 40 medical directors, finance and management staff of hospitals offering drug-resistant TB services in the country, said it had become imperative for government to increase funding, adding that donor funding for the disease had reduced significantly.

    Agbaje urged governments at all levels to look inwards and utilise local resources to care for drug-resistant tuberculosis patients.

    She also urged hospital managements to see the DR-TB programme as their responsibility.

    “They should take ownership. And going forward, over the next one or two years, we expect them to start having a budget line for DR-TB activities.

    “We expect them to start leveraging on existing resources within their facilities,” she said.

    The one-day meeting organised by IHVN was an avenue to share best practices and challenges identified within the year and strategise for better services to patients in the coming year.

    Also at the meeting, the Senior Medical Officer with the National Tuberculosis, Leprosy and Buruli Ulcer Control Programme, Dr. Babawale Victor, stressed the need for hospital managements to properly maintain wards and equipment donated by the Global Fund to Fight HIV, TB and malaria for the benefit of patients.

    “We expect that they should take adequate ownership and effectively and efficiently use the resources given to them to yield a very good result and outcome for patients that will be put on treatment,” he said.

    Dr. Idowu Joseph, who attended the meeting from State Hospital Iwo, stated that the event educated management staff on the details of the DR-TB programme to enhance their supervisory role.

    “It has opened the eyes of the chief executives to devote more time to the centers,” he said.

    The World Health Organisation figures for 2016 show that an estimated 5,200 cases of drug-resistant tuberculosis exist in Nigeria. Out of this, only 1,251 patients have commenced treatment.

  • Akwa Ibom to eradicate tuberculosis

    Akwa Ibom State Health Commissioner Dr. Dominic Ukpong has said the government will eradicate tuberculosis (TB) by 2030 under the Sustainable Developmental Goals.

    He spoke yesterday in Uyo at the launch of the tuberculosis awareness campaign by Action Health Incorporated.

    Ukpong, represented by the Permanent Secretary, Mr. Bassey Ating, noted that tuberculosis is a known chronic and debilitating disease, responsible for high level of morbidity and mortality globally.

    The commissioner said the government repositioned the Ministry of Health in ensuring that persons affected by the disease were sorted out and treated.

    Ukpong said the state tuberculosis control programme, in its activities with partners and donors, had made progress, including awareness in the media and sensitisation of health workers.

    “We must, however, emphasise that the fight to end TB is not just the fight of the government.

    “It also involves stakeholders in the community, to ensure that the disease becomes a thing of the past,” he said.

    Ukpong added that the government has stepped up its tuberculosis awareness campaign in selected local governments, including Oron, Eket and Ibeno with a high prevalence rate.

    He said the government would educate the populace and correct misconceptions about the disease.

    “We believe with this drive and sustained efforts by stakeholders, TB will be history by 2035.”

    Director/Co-Founder of Action Health Incorporated Dr. Uwemedimo Eshiet said tuberculosis was one of the top 10 causes of death worldwide.

    Eshiet, represented by Mr. Tunde Onasanya, said in 2016, 10.4 million people fell ill with TB, while 1.7 million people died from the disease.

    According to him, over 95 per cent of TB deaths occur in low and middle income countries.

    “In 2016, estimated one million children became ill with tuberculosis and about 250, 000 children died of TB, including children with HIV-associated tuberculosis.

  • Nigeria records 600,000 cases of tuberculosis annually – Minister

    Nigeria records 600,000 cases of tuberculosis annually – Minister

    The Minister of Health, Prof. Isaac Adewole, said on Friday that at least 600,000 cases of tuberculosis are recorded annually in the country.

    Adewole said the situation is quite worrisome as five out six cases of tuberculosis escaped detection.

    The stated these while flagging off a free mobile testing and treatment of the disease in Abeokuta, Ogun State.

    The initiative is tagged: “Wellness on Wheel.”

    He said Nigeria’s case represents the fourth largest burden of tuberculosis in the world.

    According to him, early detection is crucial for proper treatment while undetected cases portend grave danger to the society.

    Adewole said: “We are flagging off this initiative to improve tuberculosis cases detection in our country. Nigeria has about 600, 000 tuberculosis cases every year and we have the fourth largest burden of tuberculosis all over the world and we are number one in Africa.

    “What is particularly worrisome is that we are only able to detect one out of six cases of tuberculosis. In terms of detection, Nigeria has scored the least in the world in terms of being able to pick tuberculosis cases.

    “The danger is that tuberculosis is infective and the five out of six cases undetected will infect other people and therefore our mandate is to increase case detection, so that the five missing cases will be detected and treated, hence, this unique initiative called ‘Wellness on Wheel.’

    “With this innovative idea, we can diagnose tuberculosis within a very short time, at most, two hours. We can do x-ray using this vehicle, we can also detect tuberculosis cases using generic test, we will also know if the case is drug resistance type or non drug resistance type.”

     

  • New antibiotics, cannot combat growing threat of antimicrobial resistance – WHO

    Few new antibiotics currently in the pipeline cannot combat the growing threat of antimicrobial resistance, a World Health Organisation (WHO) report has said.

    “Most of the drugs currently in the clinical pipeline are modifications of existing classes of antibiotics and are only short-term solutions.

    “Antimicrobial resistance is a global health emergency that will seriously jeopardise progress in modern medicine,” WHO Director-General, Tedros Adhanom, said in a statement on Thursday in New York.

    “The report found very few potential treatment options for those antibiotic-resistant infections identified by WHO as posing the greatest threat to health, including drug-resistant tuberculosis which kills around 250,000 people each year.

    “There is an urgent need for more investment in research and development for antibiotic-resistant infections including Tuberculosis (TB).

    “Otherwise, we will be forced back to a time when people feared common infections and risked their lives from minor surgery,” Adhanom said.

    According to him, in addition to multidrug-resistant tuberculosis, WHO has identified 12 classes of priority pathogens.

    Some of them causing common infections such as pneumonia or urinary tract infections that are increasingly resistant to existing antibiotics and urgently in need of new treatments.

    Also, Suzanne Hill, the Director, Department of Essential Medicines at WHO, said that the report identifies 51 new antibiotics and biological in clinical development.

    According to Hill, this is to treat priority antibiotic-resistant pathogens, as well as tuberculosis and sometimes deadly diarrhoea infection Clostridium difficile.

    “Among all these candidate medicines, however, only eight are classed by WHO as innovative treatments that will add value to the current antibiotic treatment arsenal.

    “There is a serious lack of treatment options for multidrug- and extensively drug-resistant M. tuberculosis and gram-negative pathogens.

    “This includes Acinetobacter and Enterobacteriaceae (such as Klebsiella and E.coli) which can cause severe and often deadly infections that pose a particular threat in hospitals and nursing homes.

    “The report also found that though, oral antibiotics are essential for treatment outside hospitals or in resource-limited settings, few are in the pipeline.

    “Pharmaceutical companies and researchers must urgently focus on new antibiotics against certain types of extremely serious infections that can kill patients in a matter of days.

    “This is because, we have no line of defence,” Hill said.

    To counter this threat, WHO and the Drugs for Neglected Diseases Initiative (DNDi) set up a research and development partnership.

    According to Mario Raviglione, the Director of the WHO Global Tuberculosis Programme, said that research for tuberculosis was seriously underfunded, with only two new antibiotics for treatment of drug-resistant tuberculosis having reached the market in over 70 years.

    “If we are to end tuberculosis, more than 800 million dollars per year is urgently needed to fund research for new anti-tuberculosis medicines,” he said.

  • ‘I want to enable faster diagnosis for tuberculosis patient without any prick’

    ‘I want to enable faster diagnosis for tuberculosis patient without any prick’

    Dr Olanisun Olufemi Adewole, a Pulmonologist/consultant Pulmonologist at OAUTHC, and Associate Professor of Medicine at OAU, Ile-Ife was recently named as one of the ten nominees for the Innovation Prize for Africa.

    His project is a Sweat TB Test, A non-invasive rapid skin test to detect Tuberculosis Sweat TB Test. In this interview, Dr Adewole gives an insight on his innovation and how to encourage innovation in the continent

     

    Congratulations on being selected as one of the 10 nominees for Innovation Prize for Africa 2017. Were you expecting the nomination?

    Thank you. It was a rigorous process and if you have not been to someone else’s farm, you are likely to think your family farm is the biggest. Anyway, I was optimistic believing that something good will happen.

    What informed the project you submitted for consideration?

    This is what I have been working on for some time. It relates to my daily experience with patients and their care givers. This is to ensure prompt diagnosis and reduce burden associated with seeking care.

    What do you think gave you an edge to be among the top ten finalists against numerous other applicants for the prize?

    Well. I think many factors may be involved. The magnitude of the problem the innovation addresses, the out-of-the box approach; also the science behind it. I also think the likely impact of the innovation is another factor. Overall, I think Heaven smiled on it.

    In what particular way do you think your entry will contribute to addressing challenges in the continent?

    This work will enable faster diagnosis for tuberculosis patient without any prick. It is a low cost intervention that can be deployed at all levels of health especially in rural centers to support TB control programs as it is presently. And of course it will enable and serve as encouragement to local scientists to develop home grown and patient-centered solutions.

    What challenges did you have to cope with before coming up with your solution?

    It was the usual issue of scientific process. This involve many attempts before you finally reaches Eureka!

    Adapting available tools to make it suit our goal is another. But I want to state that the University and the teaching hospital were supportive, So, I’ll like to appreciate the management of the OAU and OAUTHC and my immediate boss for their support.

    What will be required for your project be easily accessible to those who need to use it?

    To achieve that; there’ll be a need to do a lot of marketing and distribution. The awareness will need to be created, and recognizing the role of regulators is also important. It is a low cost device so anyone can afford it and use it. It is a pan African solution, so scale up will start from Nigeria and gradually expand to other African countries. So we will need to leverage on existing health platforms.

    What is your advice to aspiring innovators in the country?

    First, the whole reason for innovation must not be missed out. It is about creating a significant and positive change. So aspiring innovators must reflect the change they desire in all aspects of their life.  They must be changed to be a change agent. They will need to build and develop their competencies and skills through all possible means within their reach. They must also seek to be individuals with integrity. It is character that will sustain anyone. It is important for them to also network and stand on the shoulders of giants, if they want to see far. Knowledge and wisdom come from God, so I will encourage them to seek God who is the ultimate source.

    What can the government and private sectors do to provide an enabling environment for more innovation and utilization of the new ideas?

    Let me just say that government should make it easier for innovative ideas to thrive and grow in Nigeria. Government should patronize local innovations. I also think private companies and wealthy individuals should become social/angel investors that will provide support for startup innovators.

    How do you intend to utilize the prize money if you are among the top three winners?

    The prize money will be used to spin it out of the laboratory and university. It will be used to produce the device in large quantities in order to scale up and for further research and development so that we could roll out the second generation device. Some amount will also go into training and building capacity.

    Tell us more about your background and what you have had to do to come up with this innovative project

    I am a Pulmonologist/consultant Pulmonologist at OAUTHC, and Associate Professor of Medicine at OAU, Ile-Ife. I had my basic medical degree from the University of Ibadan, where I graduated with MBBS degree in 1997. I did my internship at University College Hospital, Ibadan before proceeding for my NYSC in Kogi State and was awarded a State commendation award for excellent performance. I completed my postgraduate medical training in Internal Medicine and was awarded the Fellowship of the National Postgraduate Medical College of Nigeria in 2005. I have been working as a consultant/Lecturer at OAUTHC/OAU since 2007.

    I’ve had opportunities to travel to UK, US and other parts of the world for training. I’ve grown in my career and broadened my horizon through travel and research grants. The   innovation is a product of one of the research grants.

    I’m happily married to Temitayo and blessed with wonderful children.

    -Any other thing you think we should know about your project?

    None at the moment, other than to thank the Africa Innovation Foundation for supporting and inspiring innovators in Africa with this notable initiative.

     

  • Most TB patients in Plateau are between 15 and 54 – Commissioner

     Eighty per cent of people infected with Tuberculosis in Plateau fall within the productive age group of 15 and 54, Dr. Kuden Deyin, Commissioner for Health, said on Tuesday in Jos.

    Deyin told the News Agency of Nigeria (NAN) that the figure was based on a survey conducted by the ministry in 2016.

    “Out of 2,493 cases recorded in 2016, 1,998 of the patients, which constitute 80 per cent, were within the productive age group of 15 to 54 years; this is a great threat to the economic growth of the state,” he said.

    He said that the disease, if not controlled, would bring the the Plateau economy to its knees “in the next few years”.

    The commissioner said that Plateau had consistently paid its counterpart funds to secure free treatment for Tuberculosis patients, but regretted that some issues had made the control of the diseases rather difficult.

    He identified the issues to include inadequate equipment and manpower to clinically ascertain the correct status of suspected cases.

    Another impediment is the difficulty in accessing certain terrains, where some patients, believed to be infected with the disease, reside.

    The official suggested that the treatment and diagnosis of Tuberculosis be integrated into the main stream of the health care delivery system so that every clinic, no matter how remote, should be able to detect the micro-organism that causes the disease.

    “Such clinic should also be able to administer treatment as it is absolutely free,” he said.

    He also suggested that traditional healers and patent medicine vendors should be trained to identify the basic symptoms of the disease, pointing out that those groups were usually the first medics visited by patients in the rural areas.

    “Training the traditional healers and patent medicine dealers on how to identify the symptoms of Tuberculosis and referring them to the nearest hospital or clinic, where they can access treatment, is very fundamental to saving lives,” he said.

    The commissioner listed symptoms of the disease to include night sweat, fever, loss of weight, chest pain, difficulty in breathing and blood in the mucus, while coughing.

    Deyin advised people with such symptoms to visit the nearest hospital for prompt attention.

    He also advised patients to complete their medication to avoid complications that could result into multi-drug resistant Tuberculosis.