A non-government agency, YouthRise Nigeria, has called for urgent action by stakeholders to check overdose across the country.
The NGO, in a message to mark this year’s International Overdose Awareness Day 2025, said that in spite of efforts by government agencies, health institutions and civil society to address substance use and its impact, opioid overdose has continued to take a heavy toll on Nigerian families.
It put the number of young Nigerians said to use psychoactive substances and opioids, the leading cause of overdose fatalities, at more than 4.6 million.
It recalled how, in 2019, the Federal Ministry of Health and Social Welfare (FMoH&SW) approved the implementation of a comprehensive harm reduction programme including Needle and Syringe Programmes (NSP), Medically Assisted Therapy (MAT) and Naloxone distribution for overdose management in Nigeria.
Naloxone is an effective medication in preventing opioid overdose deaths. It is a safe, life-saving medication that can rapidly reverse the effects of opioid overdose when administered in time.
READ ALSO: 2027: Racing for keys to Agodi govt house job (2)
It said the World Health Organisation recommended that Naloxone be made widely available to those most likely to witness an overdose, including family members, peers, first responders and community health workers.
Some encouraging progress has been made through pilot community initiatives in Nigeria. Still, access remains limited, with availability largely confined to medical facilities, and a lot of work needs to be done regarding public awareness.
“Closing these gaps requires deliberate investment and policy innovation,” YouthRise Nigeria said.
“For example, supporting its community-based distribution, and ensuring adequate supply chains would expand access to those who need it most.
“Alongside this, continued investments in treatment services, stigma reduction campaigns and workforce development will strengthen the broader response to drug use and overdose.
“On this International Overdose Awareness Day, YouthRISE Nigeria affirms that Nigeria has an opportunity to lead with compassion and evidence-based policies that save lives.
“By building on existing national strategies, expanding Naloxone access, and fostering strong collaboration between government, civil society, healthcare providers and affected communities, we can ensure that every life is valued and protected.”
The theme of this year’s International Overdose Awareness Day is “One Big Family, Driven by Hope”

