Category: Family Matters

  • Heart problems and sudden death:

    Rising  incidence of  sudden cardiac death (scd) in the Nigerian  African: Possible explanations, tips on diet, exercise and   why patients who have heart related issues should   come together.

    In the past few weeks, news of Nigerians suffering sudden cardiac death(SCD) has added to the burden of uncertainties which ordinary citizens have had to bear as a result of the whiplash of the economy and other societal ailments . In their homes, on their exercise machines, even as they sleep, try to get out of bed and in hospitals all over the country , Nigerians , rich, and poor are being struck with identical disease conditions that characteristically kill the heart slowly ,steadily and suddenly . The unfortunate situation is being observed in spite of the fact that very many Nigerians frequently travel overseas to spend huge amounts of money on heart related medical issues in a manner that has forced concerned observers to describe some of these trips as medical tourism. It is not wrong for people to seek medical evaluation and treatment any where reliable facilities are available as long as the patient realizes that it is important to take into consideration the continuity of care when he comes back home. When complications declare themselves, there may be no choice other than to seek life saving help from the abandoned centers (stones that builders reject are often the ones they find suitable to hold corners of buildings). Travelling out of the country to different parts of the world for diagnosis and management of heart conditions seems to have benefitted only a limited number of Nigerians . It is time people came together and discussed the challenges patients with heart problems face so that needs assessment sheet can emerge ,with the hope perhaps they will one day make it into Government policy agenda. When a patient surfers sudden cardiac arrest (SCA), The heart can be released from what ever is responsible for stopping it from pumping blood . In extreme cases, the heart can even be operated upon without removing it from its normal anatomical enclosure while a life support machine or an artificial heart takes over the function of the heart. This can even be extended as desired to allow healing of dead or injured heart muscle (myocardium) depending on whether the procedure is being done in India, UK or America.

    Whereas compared to black people it is less likely for whites to die suddenly from Cardiac arrest, people and governments of these countries have worked very hard and have continued to do so ,to ensure that Hospitals over there have the best equipment for the diagnosis and treatment (medical and surgical) of heart conditions. They have also ensured that when patients suffer cardiac arrest , there are well equipped emergency vehicles and first respond personnel within reach to convey them to the nearest hospital as quickly as possible .

    Conditions that will lead to sudden cardiac death can remain silent for years, and when discovered, continuous evaluation and reevaluation to avoid tipping the patient into the region of death is mandatory. Very often ,the conditions imposed by travelling overseas for routing heart health care makes continuity difficult for the patient. The consequences are such that affected patients and their relations have no way whatsoever of getting help from their heart Physicians at very critical moments. On the other hand, more than half of Nigerians with manageable cardiac problems who have no means of traveling out of the country for treatment are doing remarkably well, the major problems being in the areas of access to essential medicines and adherence to drug treatment.

    The human heart like the brain and penis are richly supplied with blood vessels but the arteries in these organs do not enjoy sufficient collateralization compared to the scapula, the elbow and the knee. The arteries therefore are simply end arteries and can be easily obliterated by trauma, and disease conditions that affect their ability to respond to changes in blood rheology. Diseases of the heart and its blood vessels are called silent killers because whether or not a patient knows he has any of them, they are quite capable of precipitating cascades of death related events any where, any day and at any time. Sudden cardiac death and stroke (cerebrovascular accident) may occur as separate events or simultaneously in situations which may be much more challenging especially when in the province of physicians forced to do their shopping in resource limited countries. Sudden cardiac death may be defined as unexpected natural death from cardiac (heart) causes, occurring within a short time not up to one hour. It is not the same thing as sudden cardiac arrest (SCD) which defines a condition where a previously normal heart suddenly stops beating and patient is alive. Some authors may add a few other characteristics but these have been well documented especially for purposes of ancillary investigations and decision making.

    Contrary to what has been the belief for sometime that cardiac arrest and SCD occur more frequently in men, current evidence suggest that the number of women dying from heart attack is now coming to run parallel with that recorded for men . Recently , a young mother was dressing up a kid for school when she slumped and died .Perhaps the physical exertion of that morning coupled with flashing thoughts about traffic situation amongst others may have combined to give her heart the load that killed it. In another bad situation, a middle aged widow folded over as she shook out pieces of clothing she was looking to spread on the ropes . A third one had pain in the left side of her chest as she made to get out of bed .She was a trained medical person and a known hypertensive; yet in spite of her years of experience she ignored it and did go to work but died shortly after entering her office .

    It is perfectly normal for people to think about many issues and ask questions as they reflect on current personal efforts to keep their own mortality as far away as they possibly can.

    Space and time can only permit a few words, but the substance in a message simply providing a few explanations on the why of a common condition, and laying emphasis on paying maximum attention to family history, weight, food, drink, alcohol, caffeine, cigarettes and smoke might just be sufficient to stimulate action ,reduce anxiety and reduce the number of people dying from cardiac arrest and stroke.

    For adults, risk factors for heart attack may be arranged into two broad groups; those factors arising from the structures that make up the human body including the heart itself and those outside it.

    Further sub classifications can be made but they generally are interrelated and will include uncontrolled or poorly controlled disorders of metabolism such as hypertension and diabetes mellitus, obesity, chronic alcoholism, smoking, underlying congenital and other disease conditions of the heart(Wolf Parkinson white syndrome, viral or bacterial cardiopathy etc), blood, liver and kidney, environmental issues that cause stress in the home, office and on the roads, social and economic factors that allow the vicious cycle of suffering, poverty, ignorance and disease to subsist . Several large scale studies have shown that being a black African puts an individual at increased risk of dying suddenly from heart related issues, compared to a white person of the same age , occupation and sex. The risk is particularly higher for male Africans. Subtle but significant differences do exist between black people and whites in the mechanisms that control and regulate blood pressure and blood sodium(salt) on one hand, and the way individuals from different ethnic groups respond to therapeutic measures aimed at correcting the imbalance or derangement in the cardiovascular regulatory mechanisms at different levels in the brain(medulla oblongata), heart, the coronary blood vessels, the kidneys, the liver and the nerves including the nerves that connect the heart with the spinal cord and the Brain. Refutable data from several reports suggest that for any established disease condition of the heart ,the rate and speed of progression to sudden cardiac death differ for men and women with respect to race and ethnic category, and hence a drug designed for Japanese adult populations to mobilize salt and fluid out from body tissues into urine may not produce the desired effects when administered to Nigerian patients.

    By the middle of the third week of intrauterine life, cells that will form the human cardiovascular system will have begun to form(cardiogenic center); and at a seventh amenorrhea, a fetal heart beat can be picked up by ultrasonography. Though the conducting system of the normal heart begins at a point located in the right atrium inside a small bundle of specialized cell; the sino atrial node(SAN) passes through the AVN, the His bundle and then through the Purkinje fibers into the cardiac muscle, any sliced piece of the heart under experimental conditions is capable of contraction on it’s own for some time in a phenomenon similar to what happens when the tail of a wall gecko is cut off .Congenital abnormalities of the heart can involve all the very important portions of the heart mentioned above. In the same way anatomical variations exist in the cytoarchitecture , and other morphological characteristics of these sites as well as other very important areas of the heart including the left anterior descending coronary artery( LAD) popularly called the artery of sudden cardiac death . Consequently unique physiological and pathophysiological patterning may occur without notice in individuals with diseases of the heart. For an example,the increase in heart rate of a ten year old Chinese during a ten minute rapid results test may therefore not be the same as that of a Nigerian of the same age and gender. For similar reasons, and controlling for confounding factors, the speed and smoothness of recovery of an American male cardiac patient to a 30 minute aerobic exercise will be different compared with a black male South African of the same age . This is because at the level of signal transduction , the two important laws of Laplace and Frank Starling operate differently in blacks compared with whites. For a patient undergoing life long management for hypertension or diabetes mellitus therefore, rushing into any exercise program no matter how mild because your Doctor overseas has told you it is safe is not good enough. Cardiologists and many other categories of Physicians are very much aware of this and hence the goal usually rather than focusing on drug treatment of pathological conditions is to ensure that a patient as a whole gets well , suffering is removed and the quality of life improved. Similarly it is also unwise for a hypertensive patient to go partying all over the place eating huge quantities of food, smoking packets upon packets of cigarettes and drinking large volumes of alcohol , just because someone with a similar problem has been doing the same thing and appears to be healthy .

    TO BE CONTINUED NEXTWEEK

     

  • Home: Sweet home (2)

    DEAR Reader, last week, I showed you giving and receiving as secrets for enjoying a sweet home. This week, I will yet show you another secret, which is Thanksgiving. What is Thanksgiving? Thanksgiving is the act of giving thanks, appreciation, expression of gratitude to someone for a favour or service done. But in this context, thanksgiving is unto God, for His faithfulness. The Word of God says: It is a good thing to give thanks unto the Lord, and to sing praises unto thy name, O most High. To shew forth thy lovingkindness in the morning, and thy faithfulness every night (Psalm 92:1-2). God has done a lot for you. So, it is good that you give Him thanks. If you don’t give Him thanks, it means you are doing a bad thing. Thanksgiving is a must, for you to keep the joy of the Lord flowing in your home and family. It opens up the gates of God and ushers you into His presence, thereby granting you audience. In the excitement of the season, time must be set aside to appreciate and thank Him for His faithfulness towards you and your family, appreciation for divine protection, divine provision, divine health, unity, security, safety, promotion, etc. These are all the faithfulness of God.

    You need to spend time to think deeply and you will see that you owe God thanks. Think of His mercies and loving-kindness towards you and your family; without Him things could have been worse. Many started the year with you but not too many are alive to see the end of the year! Often times, a lot of us are so bothered about what God has not done, that we tend to forget what He has already done. The Word of God says: Bless the Lord, O my soul: and all that is within me, bless his holy name. Bless the Lord, O my soul, and forget not all his benefits (Psalm 103:1-2). Have you enjoyed God’s benefit since the year began? Don’t take God for granted. Give Him thanks.

    The fact that you are still alive is worth thanking God for. The Word of God says: Let everything that hath breath praise the Lord. Praise ye the Lord (Psalm 150:6). Do you still have breath? You owe God thanks. The scriptures says: Let everything that hath breath praise the Lord. It didn’t say, “Let everyone that has car, house, wife, husband or what have you?” You owe God thanks for your breath.

    There are a lot of things to give God thanks for. Has God done anything for you this year? If you think well, you will know that He has done so much. Thanksgiving is a commandment from God as instructed in I Thessalonians 5:18 and Ephesians 5:20. If you would want Him to continue His blessings in your life and family, read the scripture and obey His commandment. When you obey the commandment of thanksgiving, you open the door for great blessings. A life of thanksgiving is a life of sweat-less and tasteful Christian experience. If you settle down to acknowledge Him, He will acknowledge you too.

    Give God thanks for what He did yesterday, and you will compel Him to act today. You don’t have to wait for a reason to thank Him; just thank Him for who He is. When you stop having a reason to thank God, then you have created a reason to be imprisoned. There is always a reason to thank God. The Word of God says: Less the Lord, O my soul: and all that is within me, bless his holy name. Bless the Lord, O my soul, and forget not all his benefits: Who forgiveth all thine iniquities; who healeth all thy diseases; Who redeemeth thy life from destruction; who crowneth thee with lovingkindness and tender mercies (Psalm 103:1-4).

    Let the woman who has no child yet, thank God with joy in her heart for even making her a wife to a man. Let the unemployed thank God for the gift of life and health. Let the singles thank God that he or she is a qualified candidate to be married. Let the businessman that is yet to break even at the end of the year stop pointing an accusing finger at God, but thank Him for life and for being able to do business at all. In everything and for everything, give God thanks, while you are still alive! Thanksgiving unto God is better acknowledged, when you are a child of God. You become a child of God when you confess Jesus Christ as your Lord and Saviour (born again). If you would like to do so, please say this prayer: Lord Jesus Christ, I come to You today, I am a sinner. I cannot help myself. Forgive me of my sins, cleanse me with Your blood. Deliver me from sin and Satan to serve the living God. I believe You died for me and on the third day, You rose that I might be justified. I accept You as my Lord and Saviour. Make me a child of God today. Thank You for accepting me into your kingdom.

    Congratulations, you are now born again! I believe that you will begin to experience the reality of the price that Jesus paid for your sins at Calvary. All-round rest and peace are guaranteed you, in Jesus’ Name!

     

    Call or write, and share your testimonies with me through: E-mail: faithdavid@yahoo.com, faithdavid2013@gmail.com Tel. No: 08141320204; 07026385437; 07094254102

     

    For more insight, these books authored by me are available at the Dominion Bookstores in all Living Faith Churches and other leading Christian bookstores: Making Marriage Work, Marriage Covenant, Building A Successful Home and Success in Marriage (Co-Authored).

  • An Alice in Wonderland journey

    In line with the national policy of HIV testing in most developed countries, a healthy individual reactive in three different systems of testing is confirmed to be having HIV infection, even if he or she does not have any of the characteristic clinical features enumerated in the early part of this article. Other supplemental tests like western Blot (WB) test and immune fluorescence techniques are used to resolve discordant results obtained from ELISA and the rapid tests. Western blot tests were initially used as the gold standard and confirmatory test for HIV infection, but now it is used for resolving discordant screening results. It is highly specific as it detects HIV Antibodies to specific HIV protein ,the only setback being that it is expensive.

    4. Detection of Viral RNA or DNA:

    During the diagnostic window period, the individual is highly infectious but anti-HIV antibody tests will be negative. The p24 antigen or HIV RNA may be present prior to or in the early stages of seroconversion. The p24 antigen appears in the blood within two weeks of exposure and remain there for eight to twelve weeks until its corresponding antibodies appear.

    The detection of viral RNA or DNA can be done by the Polymerase Chain Reaction (PCR). This is done in laboratories with specialized equipment and personnel. In PCR, the HIV RNA/DNA bolus is amplified from blood cells. This technique can detect the virus even if only very few copies of the viral genome are present. It is highly sensitive and useful in confirming HIV in indeterminate samples of blood especially in neonates born to mothers who are seropositive. PCR based test is only used in specialized laboratories. It is costly and remain mostly as a research tool.

    The isolation of virus is done by the co-cultivation of the patients lymphocytes with fresh peripheral blood cells of healthy donors or with suitable culture lines. Eg. T-lymphomas. The presence of virus is confirmed by reverse transcriptase assays, serological tests or by changes in growth pattern of indicator cells. Viral isolation though is tedious and time consuming, and it is successful in only 70-90% of cases.

    Pediatric HIV/AIDS test is currently unpopular because we have yet to completely overcome the problems of stigma and discrimination attached to positive test results. When a woman who knows she is HIV positive is delivered of a baby , she could develop nervous breakdown if instructed not to breast feed her baby.

    For pediatric diagnosis of HIV, U.S. National Institutes of Health (NIH) working group has recommended the following criteria;

    (1) two positive HIV virology tests on separate blood samples, regardless of the infant’s age. As stated earlier the probability of having false positive tests is higher when a single blood sample is used to carry out multiple tests.

    (2) a positive HIV antibody test with confirmatory Western blot assay for those 18 months of age or older

    To rule out HIV infection, NIH recommends:

    (1) two or more negative HIV tests, one conducted at least at 4 weeks of age and the second at more than 4 months of age,

    (2) loss of HIV antibody in a child with previous HIV-negative virology assays.

    Thus, for infants less than 18 months of age, virology assays-either HIV RNA or DNA PCR-are recommended. At the time of this writing, the number of these machines in Nigeria is less than five

    Where the PCR machine is available, it has been recommended that testing should be conducted at three times: 2 to 3 weeks, 1 to 2 months, 4 to 6 months.

    For infants older than 18 months, HIV ELISA antibody assays are recommended. The world health organization(WHO) recommends a single viral detection assay at 6 weeks of age for early diagnosis of HIV infection in all HIV-exposed infants.

    Tests to determine Prognosis

    These are tests used to monitor or measure response of HIV/AID patients to management or treatment of the disease. They include: (i) HIV-antigen (ii) SerumCD4 Count (iii) Viral Load (vi) Neopterin and (v) B12- Macroglobulin. Of these tests, only serum CD4 count and HIV viral load are being routinely used.

    (i) HIV Viral Load:

    This is of greatest prognostic value and it is measured by assays which detect HIV-RNA copies .e g RT-PCR. The test has also now been established as relevant in monitoring response to antiretroviral chemotherapy. Patients with a low viral loads during the incubation period have better prognosis than those with high loads. Patients whose viral load decreases significantly immediately following commencement of antiviral therapy have better hope of recovery and better quality of life compared with those who fail to show any remarkable degree of response. Agreeably, patients with low pre-treatment viral load have better prognosis .

    (ii) CD4 Count:

    The increasing use of HIV-RNA notwithstanding, measurement of CD4 still has important value ion monitoring disease progression and the degree of response to antiretroviral chemotherapy. This is particularly true in countries where facilities for sophisticated methods are available, and so while CD4 count gives an indication of the stage of the disease, the viral load gives us an idea about the prognosis(progression).

    B. Antiretroviral Susceptibility Assays:

    Because of increasing range of ant-HIV agents available, there is increasing pressure on the provision of antiviral susceptibility assays. This has given rise to the emergence of phenotypic and Genotypic assays.

    i. Phenotypic Assay: This determines whether a particular strain of virus is sensitive or resistant to an antiretroviral agent. It determines the concentration of drug is required to inhabit the growth of the virus in the laboratory test tubes. The plaque reduction assay used in HIV cases applies only to viruses that are cultivatable. However, there is a caveat; phenotypic assay may not apply in all cases of HIV infection since some strains do not plaque in cell culture.

    ii. Genotypic Assay: This method determines mutations that are associated with resistance using molecular biology methods. These methods (in molecular biology) are complex and are not suitable for routine diagnostic laboratory services. Results are also not easy to interpret since HIV mutations occur at a furious pace such that even at the beginning of an infection resistant strains are already present.

    Interpretation Of Laboratory Results

    It is important to note that a single positive HIV test is not diagnostic for AIDS; neither is it fool proof for the presence of AIDS-related infections . Rather it should be taken only as an indication of infection with the virus. The proportion of patients with positive HIV antibody that eventually progress to AIDS differs from one geographical area to another. However, the presence of other viral or serious infections, malnutrition, overall health condition of patient and individual genetic predisposition in terms of vulnerability to persistent HIV infection are considered predisposing factors since they have been observed in association with immunosuppressant status , particularly in high risk persons.

    Unsupervised HIV testing in the clinical diagnosis of AIDS is not a simple one, especially in developing countries where the viral pandemic can occur in coexistence with other endemic tropical diseases ,confuse the clinical picture, and becloud laboratory diagnosis .A false negative HIV antibody test result in a patient with clinical AIDS, should be repeated on a fresh sample. The risk of inoculation from multiple venepunctures how ever is real and so most lab technicians continue to use the sample instead of drawing fresh blood. In this case, a negative result may be indication that the immunodeficiency is not HIV induced.

  • Coping with diseases

    Stroke is the common name for a sudden paralysis or loss of sensation caused by severe damage to some part of the brain as a result of an interruption of the blood supply to this part.

    Under normal circumstances, the demands of the brain for a continuous supply of fresh blood are so great that one-fifth or 20% of the blood pumped by the heart is delivered to the brain.

    Each artery in the brain is responsible for nourishing a particular territory and the severity of a stroke depends on which vessel is involved. An interruption of blood supply to any part of the brain causes permanent damage to the cells within about five minutes. The general arrangement of nerve fibres is such that when the right side of the brain is damaged, symptoms of paralysis and numbness affect the left side of the body and vice-versa.

    Although the outset of stroke is sudden, the underlying disease condition has usually been of long standing. In fact, little is known of the cause of stroke, except that there is a strong association with high blood pressure (that is, hypertension). Other predisposing factors are diabetes and any condition that makes thrombosis more likely. Thrombosis is the formation of a blood clot in the body and it may occur as a complication of arteriosclerosis, use of oral contraceptives and polycythemia.

    Stroke may also be caused by the lodging of a floating fragment of blood clot (known as embolus) in one of the arteries of the brain. Or it may be caused by a rupture of the wall of an artery in the brain, with escape of blood into the brain tissue. As stated earlier, the rupture of the blood vessels may be brought about by high blood pressure, forcing blood through the weakened vessel wall, as in arteriosclerosis or in aneurysm.

    The symptoms of stroke may develop instantly or over a period of several minutes. The patient usually collapses and may lose consciousness. His face may be red and there may be vomiting and convulsions. Paralysis may cripple the muscles of one side of the face, causing the mouth to be pulled to the strong side.

    Prevention and Control

    In Holistic Lifecare, it is strongly advocated that the best prospects of reducing the ill health due to stroke lies in the detection and treatment of the conditions that increase the risk. This is best accomplished by going back to Nature through dietary means of detoxifying the blood as well as strengthening the blood vessels.

    Treatment

    The patient should undergo massage and other manipulative therapies aimed at speeding the recovery of the functions of walking and speech, and the learning of day-to-day tasks. The Holistic Natural Remedy being suggested for stroke is a combination of the Natural extracts of herbs such as Allium sativum, Aristolochia albida, Picrlima nitida, Harungana madagascariensis and Viscum album.

    For further information and consultation on Holistic Lifecare research and services, especially on Blood Infections, Infertility, Sexually Transmitted Diseases, Chronic Debilitating Conditions as well as mental and social problems, please call on: 0803-330-3897 or visit: Mosebolatan Holistic Lifecare Centre, Adeyalo Layout, Ogbere-Tioya, Off Olorunsogo Express Bridge, Ibadan. Website: www.holisticlifecare.com. Distance is no barrier, we can send remedies by courier if need be. We also have facilities for accommodation, admission and hospitalization in a serene and homely environment.

  • Therapeutic uses of opioids

    OPIOIDs are used for analgesia, for moderate to severe pain. Inflammation pain and bone pain generally respond better to NSAIDs such as aspirin. Opioids may be used in the latter conditions in combination with NSAIDs. Opioids are useful for pain of surgery, trauma, and burns. Opioids used include hydrocodone (e.g., Vicodin), oxycodone (e.g., OxyContin, Percocet), morphine (e.g., Kadian, Avinza), and codeine. Hydrocodone is used in dentistry. Fentanyl IV has a short duration of action and is used in anesthesia. For labor,pethidineinjection is used.

    Opioids are useful for chronic pain, e.g. cancer pain and pain from heart disease such as myocardial infarction. Both the pain and the distress are relieved by opioids. Slow release tablets or skin patch (e.g. fentanyl) may be used.

    A few opioids with weak effects on mood and useful effects on the gut are used as medications for cough and diarrhea. Codeine suppresses the brain cough center directly and may be used as an antitussive in sub-analgesic doses. Dextromethorphan is a codeine analogue. Codeine and other opioids with more selective action on the gut are used to inhibit gut motility in people with diarrhea and may cause constipation as a side effect. Diphenoxylate(Lomotil) has more selective action on the gut and less mood effects.

    Social Uses Of Opoids

    This is the 21st century AD. I dare say that never before in history did humans want escape from reality every now and then. Life is intense, even when not full and when not abundant. Earning a livelihood and a good life is physically, mentally, and emotionally challenging in a fast paced, competitive, and materially advancing world. Social life is multifaceted with new powers of science and technology that at once can make every human a confused mutation: naked and vulnerable as well as capable and powerful. The consequences of past activities of humans on earth also haunt us with continual surprises including covert and open wars and natural disasters. Every now and then, someone feels the need to escape from these times, even if just for a short while. If spiritual advancement was commensurate or even superseded material advancement, perhaps there would be no problem, as we do recognize ourselves to be creatures of the two worlds. Our experience of the physical world is often overwhelming and overbearing, pushing us to escape. Drugs!!! Even for the ancient Egyptians, Greeks, and Romans, smoking opium gave a sense of relaxation. The thing about opioids is that they stimulate the parts of the brain (e.g. the limbic system) that mediate the emotions of reward. A person feels “high” under opium. If in the general world, you failed, you lost, you hurt, you are ashamed, you lack, you don’t want to strive…, in the world of opium, you are “high”. Users thus want to experience this pleasant feeling over and over again. Opioid narcotics provide users with a brief but pleasant escape from day-to-day undesired reality into a seeming inner “mellow”. This euphoria is however brief and the coming back to reality is painful and eventually results in a craving for the opioid.

    Users beat the law in all sorts of ways. They get and grind painkiller tablets (such as oxycodone or hydrocodone) and snort the powder. It was reported that in 2010 in the USA, for example, 6.6 percent of high school seniors took cough syrup “to get high.” Cough syrup contains the opioid dextromethorphan which at high doses can give a dissociative or out-of-body experience. The law and its collaborators in the industry are looking for means to counteract abuse of prescription pain medications. Chemists are developing opioid pills that contain niacin, which can cause unpleasant flushing, rapid heart rate and nausea if taken at the dose the tablets supply when crushed and snorted but not when swallowed. Chemists are also trying to include coated pellets of naltrexone, an opioid blocker, in regular opioid pills. If the pills are taken as oral medication, the pellets will pass through the body and be excreted. If the pills are crushed by abusers for snorting, the naloxone will be released and prevent the abuser from experiencing the opioid “high”. Opioid pills are also being manufactured as slow release gel caps which are processed only lower in the gut and must reach there to be effective.

    Narcotics are in high demand and bring in a lot of money for big business. Understanding why people use narcotics, how they obtain narcotics, and all the good and evil consequences of using narcotics can help us avoid catastrophic health problems in our families. If however a member of the family becomes addicted, we need to support the person in passing through painful withdrawal and detoxification through a licit medical setup or program. However a holistic approach includes examining and counteracting the social realities that led to drug escapism.

    Dr. ‘Bola John is a biomedical scientist based in Nigeria and in the USA. For any comments or questions on this column, please email bolajohnwritings@yahoo.com or call 07028338910 or 08160944635

  • Tips for taking care of oily skin

    If you have dry skin, your complexion may look dull or lackluster. Wrinkles and lines develop more easily when you have dry skin. The following are tips for taking care of dry skin:

    Wash your face twice a day, once in the morning and once before bed. Washing more often can strip your skin of all the natural moisturizers and increase oil production. The only time you should wash your face more than twice a day is if you have been perspiring.

    •Keep showers and baths warm, not hot. Hot water strips your skin of natural moisturizers and dry it out. While a long, hot shower feels good, for those with dry skin, shorter (5 to 10 minutes) and warm showers will help keep your skin moisturized.

    •Stay away from harsh soaps and cleansers. Stick with non-soap, fragrance-free cleansers. Stay away from those with antibacterial and other additives.

    •Use a moisturizer after you shower. After your shower, pat your skin dry and apply a moisturizer. This helps lock in moisture. If you apply moisturizer during the day, splash a little water on your skin before applying the moisturizer.

    •Try different moisturizers to find the one that is right for your skin. There are hundreds of moisturizers and it is hard to know what is right for your skin. You may need to try a few different ones, but look for those specifically made for dry skin.

    •Use a shaving cream or gel. When you shave, you are also taking the skins natural oils away. Shave after your shower, when your hair is wet and softer.

    •If you use a toner, use it only on areas that are oily, such as your forehead or around your nose. If you have areas that aren’t oily, toners can create dry patches.

    •Stop smoking. Smoking dries out your skin and causes premature aging.

    •Drink plenty of water. Our bodies hydrate from the inside out. If you aren’t drinking enough water, it can show up on your skin. Drink the eight recommended glasses of water each day to keep your skin smooth.

    •Don’t forget moisturizer for areas where the skin is thinner and can easily dry out. This includes around the eyes and the neck.

    •Exfoliate. This removes the dead skin cells on your face. When you are finished exfoliating, immediately apply moisturizer. This allows the moisturizer to reach the live skin cells and penetrate into the skin.

    •No matter how tempted, don’t pick, pop or squeeze pimples as it can cause scarring and leave red spots on your face.

  • Home: sweet home

    Dear Reader, you are welcome to December, the Christmas month. It is the month when we look forward to celebrating the birth of our Lord and Saviour Jesus Christ. It is the month to recount God’s goodness, His mercy, and all His wonderful blessings since the beginning of the year.

    It is the festive period of the year when we must enjoy together as a family. Therefore, this month, I shall be teaching on those things that will make your home sweet at Christmas. This week, I want to teach on Giving and Receiving.

    I want you to know that Christmas season is a time to receive and share God’s love. The Word of God says: For God so loved the world that he gave his only begotten Son, that whoever believes in him should not perish, but have everlasting life (John 3:16).

    God is a God that delights in giving and sharing. The Gift of His Son, Jesus Christ is an everyday addition to the world and humanity in general. His works of creation, like the trees, sun, moon, star, water, rain, plants, animals, fishes, etc, are blessings to man. One way to keep joy in the family long after Christmas, is for members of the family to express love by giving and sharing everyday, even after Christmas is over.

    Many people often find the heart to give only at Christmas, but this should not be so. Giving and sharing should be an everyday practice. The volume of what you give is not what matters, but the heart behind your giving and sharing is what matters.

    Giving and sharing are not limited to gifts, but acts of love, helps and service which should be rendered to others. You may not have money or material things to give, but a word of compliment, a commendation, a helping hand or even a smile will go a long way.

    At the time when Jesus Christ was born, He received material gifts from the three wise men from the East. The Word of God says: Now when Jesus was born in Bethlehem of Judaea in the days of Herod the king, behold, there came wise men from the east to Jerusalem, Saying, Where is he that is born King of the Jews? For we have seen his star in the east, and are come to worship him. And when they were come into the house, they saw the young child with Mary his mother, and fell down, and worshipped him: and when they had opened their treasures, they presented unto him gifts; gold, and frankincense, and myrrh (Matthew 2:1-2, 11).

    Jesus Christ, all through His lifetime here, was a gift to mankind and was an everyday giver. He gave eyes to the blind, health to the sick, hope to the hopeless and helps to the helpless. The act of giving and sharing towards your family, the needy, the poor and helpless should be done all through the year and not just at Christmas only.

    One of the secrets of giving is that when you give or share something with someone else, you make that person happy and you create room for someone else to make you happy. What you sow is what you reap. When you give those who are not in position to give you back, like the less privileged, needy or poor, you create room for God to bless you. Usually, when God pays back, He pays back in ways that no man can ever pay you. The Word of God says: Give, and it shall be given unto you; good measure, pressed down, and shaken together, and running over, shall men give into your bosom. For with the same measure that ye mete withal it shall be measured to you again (Luke 6:38).

    Knowing Christ is the foundation for enjoying a sweet home. This comes by confessing your sins and accepting Jesus as your Lord and Saviour. If you are ready to be born again, please say this prayer: Dear Lord Jesus Christ, I come to You today as a sinner. Forgive me of my Sins. I believe You died and rose on the third day for my sins. I accept You as my Lord and Saviour. Make me a child of God today. Thank You for accepting me into Your kingdom.

    Congratulations, you are now born again! I believe that you will begin to experience the reality of the price that Jesus paid for your sins at Calvary. All-round rest and peace are guaranteed you, in Jesus’ Name!

    Call or write, and share your testimonies with me through: E-mail: faithdavid@yahoo.com, faithdavid2013@gmail.com Tel. No: 08141320204; 07026385437; 07094254102

    For more insight, these books authored by me are available at the Dominion Bookstores in all Living Faith Churches and other leading Christian bookstores: Making Marriage Work, Marriage Covenant, Building A Successful Home and Success in Marriage (Co-Authored).

  • Marriage: A garden of treasures

    Dear Reader, one common treasure in any healthy garden that is well cared for, is healthy fruits. This is so too, in every marriage garden that is well cared for, following the laid down principles given by God.

    Marriage fruitfulness is a guaranteed treasure in your marriage garden. God Himself commanded this to be, the way He commanded creation to be, immediately after He conducted the first wedding ever in Genesis 1:28 which says: And God blessed them, and God said unto them, Be fruitful, and multiply, and replenish the earth, and subdue it: and have dominion…

    It was not an admonition, but a treasure added to the marriage garden. God did not say, “You may be fruitful”, but “Be fruitful!” God designed your marriage to be fruitful and He has not changed His design either. Whatever contrary and negative report you may be experiencing now is of the devil, which must be forcefully taken back via an understanding of the treasures of fruitfulness that God has made available unto you. I command every such report to be cancelled today, by the Blood of Jesus!

    Though unfruitfulness is a problem plaguing many marriages today, I want you to know that your marriage was designed for fruitfulness. It should be a natural blessing, addition and favour from God to you in your marriage garden. Everything He created came to be and is still in existence today. God will not lie nor change. He is not a respecter of persons but His Word (Acts 10:34). His counsel stands sure forever (Psalm 33:11). If He said, Let there be light and there was light, then when He said, Be fruitful, you must be fruitful.

    No biological or any other report from man has the power to keep your marriage garden fruitless. Mark 10:27 says: With men it is impossible, but not with God: for with God all things are possible. Disabuse your mind of every scientific explanation. Trust God by holding Him to His Word, and you shall receive a miracle. Your marriage garden was meant to bear treasure fruits, as written in Deuteronomy 7:13-14. Instead of mourning and weeping over negative reports, wipe your tears and start enriching your mind with the covenant rights of your marriage garden.

    Choose to walk in the knowledge of the revealed truth and you will soon find out that no force can hold you down anymore. I see every stranger in your body die from its root and all that may have mocked you before will gather to rejoice with you. All that called you barren, will soon call you the happy mother of children in the name of Jesus!

    These testimonies are proofs of God’s power over every contrary report to His Word: “My sister got married in 1972 and in 1993, there was still no child. This thing kept bothering me. In 1990, I gave my life to Christ. Since then, God has been blessing me tremendously via His Word.

    One day, I heard His Word said to me, ‘God is never late’. This word went straight into my system and calmed me down.

    I woke up that day with a heavy heart because I remembered my sister’s situation, which had been for the past 20 years. I agreed on the Word of God as it came. To the glory of God my sister took in a month after and gave birth to a bouncing baby boy!” Adelakun, T.B.

    “I have just delivered a bouncing baby boy 14 days ago. When I was pregnant, despite the Word of God that I had been hearing, the devil kept telling me lies and wanted to deceive me. I was passing blood for the first four months and a half of my pregnancy! In order not to be embarrassed by being stained, I had to use pad.

    In all these, I kept holding on to God’s Word. I kept on confessing that it was just blood that I was seeing, not my baby and that the presence of the Holy Spirit is holding this baby in my womb. I believed my confessions.

    When the pregnancy was almost five months, the bleeding stopped. I did not go to the clinic until after seven months and two months later, I delivered a baby boy!”- Jayeoba M.

    By the power backing the Word I bring to you right now, that situation of barrenness is consumed and you are liberated, in Jesus’ name. Your testimony shall be the next. You are free in Jesus’ name!

    However, children are from the Lord (Psalm 127:3) and accepting Jesus Christ into your life will guarantee you access to His reward. To accept Jesus, please say this prayer: “Lord Jesus Christ, I come to You today. I am sinner. I cannot help myself. Forgive me of my sins and cleanse me with Your blood. Deliver me form sin and Satan to serve the living God. I believe You died for me and on the third day, You rose that I might be justified. I accept You as my Lord and Saviour. Make me a child of God today. Thank You for accepting me into Your kingdom.

    Congratulations, you are now born again! I believe that you will begin to experience the reality of the price that Jesus paid for your sins at Calvary. All-round rest and peace are guaranteed you, in Jesus’ Name!

    Call or write, and share your testimonies with me through: E-mail: faithdavid@yahoo.com, faithdavid2013@gmail.com Tel. No: 08141320204; 07026385437; 07094254102

    For more insight, these books authored by me are available at the Dominion Bookstores in all Living Faith Churches and other leading Christian bookstores: Making Marriage Work, Marriage Covenant, Building A Successful Home and Success in Marriage (Co-Authored).

  • An Alice in Wonderland

    In Nigeria, a major problem affecting research in HIV/AIDS is getting reliable data. The reasons are protean; governments at all levels are prepared to release millions and billions of Naira to entertainers and sports enthusiasts without any bureaucratic hurdles as if giving out millions of Naira to celebrities is what the people elected them for. Imagine an elected state Governor giving out as much as 3000US dollars each to participants in the recently concluded ‘BBA(big brother Africa) the chase”; an event that showcased arrant immorality to unimaginable levels. Where did the money come from? People have become so incapacitated that they simply grumble in resignation. These same government officials are notorious for treating issues concerning health and education with so much non chalance that those who are writing have acknowledged that indeed history is being made ; with strange and unusual actors appearing on the stage to the awe and amazement of every Nigerian; young and old . It is relevant to emphasize that aside from the ongoing strikes by university lecturers(ASUU) and Resident Doctors(ARD), some states have witnessed more strikes by certain organized groups compared with others. People like Professor Osibanjo instead of asking for proof that ASUU has done anything by way of research to help the country should ask him self the same question, even as the head of a colossal institution the activities of which are permanently under discussion. He should then go ahead and midwife a law making it mandatory for all public office holders including political office holders to pass through thorough medical investigations including neuropsychiatric evaluation, so that individuals found to have issues with mentation can be identified and possibly disqualified by INEC. If he can do that for this country then he will be held with the same measure of reverence that was given. He should actually be seen to be very worried about the general state of lawlessness in the country, instead of making inuring and contradictory statements . The late Gani fawehimin never minced words; on important national issues, he made his position clear and unambiguous. We should have elder statesmen like that . He fought a good fight while he lived and left it all for Nigerians. It is abnormal for any one entrusted with the lives of other human beings in the same country to exhibit what in the language of Psychiatrist as a flat affect . It is even better when a leader surfers flares of emotion, but to be so flat as if communing with alien world is at best consistent with paranoia.

    Unfortunately for the poor in this country, even when Government manages to release funds with support from foreign donor agencies, corruption takes control and so nothing works . Every dispensation and every now and then, one slogan succeeds another; ‘Health for all by the year 2000”, MDGS, vision 20.2020, etc. and nothing comes out of the billions pumped into them.

    The medical , moral and legal basis for AIDS screening tests in a number of cases is antibody detection and once established and confirmed in a reliable laboratory, HIV antibody levels will persist throughout the life of the infected person . It has nothing to do with God or Satan. In fact, it is not the will of God that the situation of antibody production in response to the presence of HIV be reversed or undone . The presence of antibody simply means that the patient is assumed to be infected and can infect others ; it does not in any way imply immunity, sleeping around when you are HIV positive whether or not you use male or female condom and are on ART is profoundly irresponsible and dangerous.

    What may inform the need to run HIV/AIDS tests?

    There are a number of situations that may warrant lab tests for HIV/AIDS;

    .Before any surgery

    .During pregnancy (as part of routine antenatal care)

    . In procedures like endosccopy, laparoscopy, dialysis( including ambulatory peritoneal dialysis , artificial reproduction procedures(ART), before transfusion of blood or blood products, , blood and organ donation .It is in the patients’ interest to ensure it is the practice in centers offering these services before submitting themselves for instrumentation.

    .Lab test for HIV/AIDS can also be necessary as usual requirements for marriage, cases of rape to establish pre HIV incubation period status.

    .The test is also commonly requested when some clinical conditions emerge that point in the direction of AIDS such as unexplained high or mild elevation of body temperature depending on the HIV subtype) that may have lasted for over a month with disappointing response to the usual drugs for fever associated disease conditions

    “Unexplained weight loss (beyond 10% of body weight) within the setting of a medical history of chronic diarrhea

    “Unusual mouth diseases that were never there before the characteristic symptoms appeared

    “Appearance of eye diseases that look like vernal conjunctivitis( popularly referred to as ( Appolo) but this type is accompanied with much redness and plenty of gummy discharge-christened ‘salad cream and tomato ketchup retinopathy” as observed via ophthalmoscope.

    “Skin manifestations-boils and weeping lesions

    “Yellow eyes with or without pain in the right upper abdomen below the chest when there is co infection with hepatitis

    “Brain tissue, involvement is seen commonly these times with Neuro psychiatric manifestations or episodes of seizure and vomiting

    Others conditions that could draw attention to the possibility of HIV/AIDS being present include ;- Pseudomembranous type oral Candidiasis, Angular cheilosis, Xerostomia-dry mouth, marked reduction in the quantity of saliva expressed from whartsons or stensons ducts

    Also , HIV is commonly found in individuals suffering from pneumocystic pneumonia or pulmonary tuberculosis, syphilis, cytomegalovirus infection, herpes simplex, varicella-zoster, candidiasis, particularly oral with the candida sp.

    Though not common, AIDS defining cancers-such as -karposis sarcoma including asymptomatic oral karposis have been documented, as has AIDS related lymphoma

    What do we take home from all these ?

    A medical person cal take a look at you when you go to the Clinic for something else and then insist that you run certain lab tests in addition to HIV/AIDS test. While you may be surprised ,it will be unwise to do otherwise .It could be a stitch in time. You should feel free to ask questions however uncomfortable it may seem. A small fleshy swelling, firm to hard, swelling that appeared under the skin of the back of the head below the ear , and since it was noticed has refused to go away despite all efforts may have been ignored, but your Doctor might need to see that swelling.

    Many patients are now aware of these and many more others that can be tied to the possible presence of HIV/AIDS.

    Clinical suspicion for HIV/AIDS should be higher in the following individuals viz;

    People who are sexually active and have had unprotected sex in the past few years

    Blood recipients , particularly recipients of multiple blood units, other blood products like plasma ,platelets, even if blood was screened

    Organ recipients ,

    Intravenous drug users, especially those who share needles and syringes

    People with multiple partners- not only having many men or many women, but going from one failed marriage to another

    Individuals in polygamous and polyandrous relationships

    Tattoo and piercing enthusiasts etc, etc.

    In the absence of effective, uniform and harmonized HIV/AIDS voluntary counseling and testing policy, problems are unavoidable. Some of these problems are also connected with the rising proportion of illiterate Nigerians. Even the educated seem not to be firm about what they know concerning HIV/AIDS lab tests

    Some of the questions encountered can be summarized as here under;

    What is the test all about? How is it done? Where exactly do you get a reliable test? What is counseling? Why does any one need counseling? How do you explain false positive and false negative tests? What happens when an individual is said to have borderline HIV/AIDS? How is HIV test interpreted?

  • Together, at Home and at Work

    Together, at Home and at Work

    I spent much of the last six months helping my wife with a rare professional opportunity. When friends heard how many days, nights and weekends we spent in the same room, they had the same reply: “Whoa! When are you getting divorced?”

    It reminded me of when my mother, an art teacher by training, helped my father, a real estate developer, build houses when I was young. She described the experience as “the worst years of our marriage.”

    People who don’t work with their spouses look at those who do in the same way that casual fans often look at professional hockey: Sure, it’s fun for a while, but when is the fight going to break out?

    One reason for this hostility may be decades of negative examples. There are some high-profile couples who work together successfully. Bill and Melinda Gates run their foundation, as do Bill and Hillary Clinton (along with Chelsea). Nina and Tim Zagat built their restaurant-guide empire together, as did Kate and Andy Spade in fashion. Joel Coen has directed his wife, Frances McDormand, in four films; Daniel Craig and Rachel Weisz are performing together on Broadway now.

    But the list of famous couples who worked together and flamed out is even longer. In Hollywood: Richard Burton and Elizabeth Taylor, Lucille Ball and Desi Arnaz, Woody Allen and Diane Keaton (and later Mr. Allen and Mia Farrow), Tom Cruise and Nicole Kidman.

    In music: Sonny and Cher; James Taylor and Carly Simon; Tammy Wynette and George Jones; the two couples in Abba, both now divorced. And elsewhere: Tammy Faye and Jim Bakker; Rupert Murdoch with both his second wife, Anna, and his third, Wendi; Frank and Jamie McCourt, whose split forced them to sell the Los Angeles Dodgers. It’s a wonder anyone says “I do” and then sets foot in the same office as their spouse.

    Exact numbers of collaborating spouses are hard to come by. For almost 20 years, Glenn Muske, a professor at North Dakota State University, has studied couples who start businesses together. He calls them “co-preneurs” and said his research found that two-thirds of businesses in the United States are family owned, and a third of those are run by couples. Other arrangements include romantic partners who work in the same organization but not alongside each other, and sole proprietors who get casual, often unpaid contributions from their spouses.

    So what can a working couple do to avoid disasters? I reached out to some of those who have researched the matter.

    DON’T COMPROMISE Kathy Marshack, a psychologist in Vancouver, Wash., and the author of “Entrepreneurial Couples,” said that couples working together was the norm for most of human history, from family farms to mom-and-pop shops. Blaming the arrangement for an increase in fighting is wrong, she said.

    “This real issue is that with increased time together, you have more time for conflict,” she said.

    Lots of people experience an uptick of fighting on vacation, she said. “Suddenly you’re spending every day together,” she said. “You’re having fun, but you’re sick and tired of the fact that the other person leaves the towel on the bed or whatever.”

    Dr. Marshack said that the biggest problem she sees is that the skills it takes to succeed in a relationship, like accommodation, are often destructive in business.

    “Most Americans expect their love relationship to be between consenting partners,” she said. “But at work it’s different.”

    To accomplish things in the workplace, she said, someone needs to be in charge, or, even better, each person needs to have control over separate things: say, one person controls strategic decisions and the other financial ones.

    “At work I always tell people never compromise unless you absolutely have to,” she said. “When you’re working with your spouse, you’re going to be tempted to compromise, because that’s what you do at home. But that’s not good for business.”

    Too much sensitivity to others is the primary reason family companies grow slower than nonfamily firms, she said.

    DON’T SET BOUNDARIES One problem my wife, Linda, and I have faced is that when you’re living, working and raising children together, a disagreement about one aspect of your lives quickly descends into an excuse to bring up everything else that’s bothering you. “You don’t like that decision I made about that project? Yeah, but you never finished the dishes last night.”

    Researchers call that phenomenon “spillover.” The easy response is to create clear boundaries: no business in the kitchen, or no talk about the children during office hours. But Phyllis Moen, a sociology professor at the University of Minnesota who has studied working couples for decades, said that approach is outdated.

    “These days, everyone experiences blurring of boundaries because of new technologies,” she said. Co-working couples have an edge, she said: the partners understand the reason for the interruption and are right there to help solve it.

    “Otherwise, pressures at work get translated to stress at home, and no one understands why,” Dr. Moen said.

    Her advice: When issues pop up at inappropriate times, dispense with them quickly, then get back to what you’re focusing on, like negotiating your office lease or playing Monopoly with the kids.

    DON’T FEAR CONFLICT Joshua Wolf Shenk, a best-selling author, has spent the last few years studying creative pairs for his forthcoming book, “Powers of Two.” His subjects include nonromantic partners like John Lennon and Paul McCartney, as well as romantic ones like Marie and Pierre Curie, and Giancarlo Giammetti and Valentino. He said that instead of viewing conflict as threatening, co-working spouses should view it as elemental to their success.

    “A lot of people mean conflict as bouncing up against someone in a way that is not pleasurable,” he said. “But the core experience is that bouncing up against someone.”

    To have chemistry, he said, you have to have rapport and a unity of vision.

    “But there have to be fundamental differences, or else the two people have nothing to add to each other,” he said.

    Mr. Shenk likened conflict between partners to a tennis match where you’re both hitting the ball as hard as you can. “You have a net, you have a perimeter, you step onto the court, you’re able to step off the court,” he said. When the relationship works, he said, the sense of mutual commitment is strong enough that it leads to a sense of shared reward. Take note, co-working couples: Fight on!

    DON’T HESITATE TO WALK AWAY What happens when working and living together become unsustainable? Dr. Muske said that most people, though not all, tend to try to save the relationship first. This sometimes requires that somebody be dismissed.

    “You can easily give a pink slip to an employee,” he said, “but if you’re living with that person, you have to reach a mutual understanding that this is not working.”

    He recommends being clear in advance: both spouses have the right to tell the other that he or she is holding the organization back. My wife, who works with entrepreneurs, calls this a “start-up prenup.”

    I asked Linda what she had learned from our experience. While acknowledging the occasional tensions, she was, as is her nature, upbeat: “Working together allowed me to have a deeper appreciation for what you do, and the same in reverse.”

    Would she recommend it to others?

    “For a limited time,” she said.

    That qualified support echoes what I’ve heard time and again. For all the problems, most co-working couples enjoy the process. One reason may be that regardless of how well their businesses do, couples who spend that much time together tend to think more about their relationship.

    Dr. Marshack said: “When you work with your spouse, you’re going to be challenged all the time by the way they think, including the way they think about you. That makes you introspective. It makes you work on yourself and the relationship. And that can’t be bad.”

     

    Culled from NYtimes